Endocrine Abstracts

Introduction: The limit of quantification (LOQ) is defined as the lowest analyte concentration that can be reproducibly measured with defined imprecision expressed as CV (coefficient of variation). Low concentrations of hormones estradiol, LH, FSH and testosterone are essential in diagnosis and monitoring of various endocrine disorders. Automated immunoassays have well known advantages, but still limited in achieving necessary analytical sensitivity. The major concern is to pr...

Introduction: Biological variation (BV) data describe the variability of clinically important measurands around homeostatic set points within subjects (CVI) and between subjects (CVG). The availability of well characterized data enables the interpretation of laboratory results in clinical settings and can also be used to define analytical performance specifications. The aim of this study was to deliver BV estimates for anti-Müllerian hormone (AMH) and androstenedione amon...